Control of ovulation


All patients are administered hormones to stimulate ovulation. These hormones are generally administered subcutaneously and started on first few days of the cycle. The dose may vary from one patient to another and from one cycle to another. Treatment is continued until correct maturation of one or more ovules is attained. Proper control of ovulation is crucial to prevent and avoid excessive risks and to determine with greater accuracy the day of ovulation.

Ovulation is controlled with the following tests:

  • Vaginal ultrasound:
    This is used to view the ovaries and to verify the size and growth rate of the follicle in one of these (the ovule is inside the follicle). The size of the follicle increases as it matures. They are considered mature or ready to ovulate when they reach a minimum size of 18 millimetres in diameter.
  • Blood test: 
    This is used to check blood estrogen (estradiol) levels. This female hormone is produced in the ovaries and the levels increase as the ovule grows inside the follicle. This can be used to evaluate the response when ovulation stimulation treatment.

The first test is conducted between 4 to 6 days after the initial stimulation treatment, generally on day 8 of cycle. Depending on how the ovaries respond to the treatment, the date of the next control and the dose necessary are established. Once one or more follicles are fully mature, a fixed dose of 5000 IU of human chorionic gonadotropin hormone is administered and insemination conducted between 36 and 42 hours later.

On average, 3 to 4 controls are generally conducted per cycle. There is a lapse of about 4 to 8 days between the first control and day of insemination.


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